2023 Publications

Threat and reward imminence processing in the human brain

V. P. S. Murty, D,. Song, S,. Surampudi, G, S., Pessoa, L., (2023) Threat and reward imminence processing in the human brain.

How many brain regions are needed to elucidate the neural bases of fear and anxiety?

Pessoa, L., (2023). How many brain regions are needed to elucidate the neural bases of fear and anxiety?. Neuroscience & Biobehavoiral Reviews. 146.


The Entangled Brain

Pessoa, L., (2023). The Entangled Brain. Journal of Cognitive Neuroscience. 35(3). 349-360. 

Disentangling Some Conceptual Knots

L. Pessoa., (2023). Disentangling Some Conceptual Knots. Journal of Cognitive Neuroscience. 35(3). 391-395. 

Mind as Motion: Patterns of Psychology to Neurobiology

Hipolito, I., van Geert, P.  Pessoa, L., (2023). Mind as Motion: Patterns of Psychology to Neurobiology. Psycharix. 

2022 Publications

Distributed and Multifaceted Effects of Threat and Safety

Dinavahi V. P. S. Murty, Songtao Song, Kelly Morrow, Jongwan Kim, Kesong Hu, Luiz Pessoa; Distributed and Multifaceted Effects of Threat and Safety. J Cogn Neurosci 2022

Multimodal measures of spontaneous brain activity reveals bothcommon and divergent patterns of cortical functional organization

Vafaii, H., Mandino, F., Desrosiers-Grégoire, G., O’Connor, D., Shen, X., Ge, X., Herman, P., Hyder, F., Papademetris, X., Chakravarty, M., Crair, M. C., Constable, R. T., Lake, E. MR., & Pessoa, L. (2023). Multimodal measures of spontaneous brain activity reveals both common and divergent patterns of cortical functional organization. BioRxiv, 2022.

Refocusing neuroscience: moving awayfrom mental categories and towardscomplex behaviours

Pessoa, L., Medina, L., & Desfilis, E. (2022). Philosophical Transactions of the Royal Society B: Biological Sciences.

Controversies and progress on standardization of large-scale brain network nomenclature

Uddin, L. Q., Betzel, R. F., Cohen, J. R., Damoiseaux, J. S., De Brigard, F., Eickhoff, S., … Spreng, R. N. (2022, March 8). 

Emergent processes in cognitive-emotionalinteractions

Luiz Pessoa (2010). Dialogues in Clinical Neuroscience

A call for more clarity around causality in neuroscience

David L. Barack, Earl K. Miller, Christopher I. Moore, Adam M. Packer, Luiz Pessoa, Lauren N. Ross, and Nicole C. Rust (2022). Trends in Neurosciences.

The Entangled Brain

Luiz Pessoa (2022). MIT Press

2021 Publications

How representative are neuroimaging samples? Large-scale evidence for trait anxiety differences between fMRI and behaviour-only research participants

Charpentier, CJFaulkner, PPool, ERLy, VTollenaar, MSKluen, LMFransen, A; … O’Doherty, JP; (2021), Social Cognitive and Affective Neuroscience, 16, 1057-1070.

To pool or not to pool: Can we ignore cross-trial variability in FMRI?

Gang Chen, Srikanth Padmala, Yi Chen, Paul A. Taylor, Robert W. Cox, Luiz Pessoa (2021), NeuroImage.

Geodesic distance on optimally regularized functional connectomes uncovers individual fingerprints

Kausar Abbas, Mintao Liu, Manasij Venkatesh, Enrico Amico, Alan David Kaplan, Mario Ventresca, Luiz Pessoa, Jaroslaw Harezlak, Joaquín Goñi (2021), Brain Connectivity, 11, 333-348.

Lessons from Leslie: A tribute to an extrodinary scientist and mentor

Elizabeth A Buffalo, Susan M Courtney, Peter De Weerd, Julien Doyon, Yang Jiang, Avi Karni, Sabine Kastner, Luiz Pessoa, Andrew Rossi (2021), Trends in Neurosciences, 44, 241-243.


Refocusing neuroscience: moving away from mental categories and towards complex behaviours

Pessoa, L., Medina, L., & Desfilis, E. (2021), Philosophical Transactions of the Royal Society B.

Controllability over stressor decreases responses in key threat-related brain areas

Chriag Limbachia, Kelly Morrow, Anastasiia Khibovska, Christian Meyer, Srikanth Padmala, and Luiz Pessoa (2021),
Communication Biology.

Distributed and multifaceted effects of threat and safety

Kelly Morrow, Murty Dinavahi, Jongwan Kim, Song-tao Song, Kesong Hu, Luiz Pessoa (2021),
Journal of Cognitive Neuroscience, 1-22.

Sources of information waste in neuroimaging: mishandling structures, thinking dichotomously, and over-reducing data

Gang Chen, Paul A. Taylor, Joel Stoddard, Robert W. Cox, Peter A. Bandettini, Luiz Pessoa. (2021), BioRxiv.

Learning brain dynamics for decoding and predicting individual differences

Pessoa, L., Limbachia, C., Misra, J., Surampudi, S. G., Venkatesh, M., & Jaja, J. (2021), PLOS Computational Biolology.

2020 Publications

Fighting or embracing multiplicity in neuroimaging? neighborhood leverage versus global calibration

Chen, G., Taylor, P. A., Cox, R. W., & Pessoa, L. (2020), NeuroImage.

Emotion in future intelligent machines

Belkaid, M., & Pessoa, L. (2020), ArXiv.

Neuropsychologia special issue editorial: The neural basis of emotion

Hamann, S., Pessoa, L., & Wager, T. D. (2020), Neuropsychologia.

Interactions between emotion and action in the brain

Lima Portugal, L. C., Alves, R. de, Junior, O. F., Sanchez, T. A., Mocaiber, I., Volchan, E., Smith Erthal, F., David, I. A., Kim, J., Oliveira, L., Padmala, S., Chen, G., Pessoa, L., & Pereira, M. G. (2020), NeuroImage.

2019 Publications

Neural architecture of the vertebrate brain: implications for the interaction between emotion and cognition

Pessoa, L., Medina, L., Hof, P., Desfilis, E. (2019), Neuroscience & Biobehavioral Reviews, 107, 296-312.

Representational organization of novel task sets during proactive encoding

Palenciano, A., González-García, C., Arco, J., Pessoa, L., Ruz, M. (2019), The Journal of Neuroscience,

What drives prioritized visual processing? A motivational relevance account

Maratos, F., Pessoa, L. (2019), Progress in Brain Research, 247, 111-148.

An integrative Bayesian approach to matrix-based analysis in neuroimaging

Chen, G., Bürkner, P‐C., Taylor, P., …, Cox, R., Pessoa, L. (2019), Human Brain Mapping, 40, 4072– 4090.

Dynamic threat processing

Meyer, C., Spadmala, S., Pessoa, L. (2019), Journal of Cognitive Neuroscience, 31, 522-542.

2018 Publications

Information about peer choices shapes human risky decision-making

Tomova, L., Pessoa, L. (2018), Scientific Reports, 8.

Attentional capture by simultaneous pleasant and unpleasant emotional distractors

Padmala, S., Sambuco, N., Codispoti, M., Pessoa, L. (2018), Emotion, 8, 1189-1194.

LEICA: Laplacian eigenmaps for group ICA decomposition of fMRI data

Liu, C., JaJa, J., Pessoa, L. (2018), NeuroImage, 169, 363-373.

Robot cognition requires machines that both think and feel

Pessoa, L. (2018), Aeon.

Understanding emotion with brain networks

Pessoa, L. (2018), Current Opinion in Behavioral Sciences, 19, 19-25.

Altered segregation between task-positive and task-negative regions in mild traumatic brain injury

Sours, C., Kinnison, J., Padmala, S., Gullapalli, R.P., Pessoa, L. (2018), Brain Imaging and Behavior, 12, 697-709.

2017 Publications

Cognitive-motivational interactions: Beyond boxes-and-arrows models of the mind-brain

Pessoa, L. (2017), Motivation Science, 3, 287-303.

Dynamics of intersubject brain networks during anxious anticipation

Najafi, M., Kinnison, J., Pessoa, L. (2017), Frontiers in Human Neuroscience.

Do Intelligent Robots Need Emotion?

Pessoa, L. (2017), Trends in Cognitive Sciences, 21, 817-819.

Cognitive Control and Emotional Processing

Pessoa, L. (2017), The Wiley Handbook of Cognitive Control, 392-407.

Potential reward reduces the adverse impact of negative distractor stimuli

Padmala, S., Sirbu, M., Pessoa, L. (2017), Social Cognitive and Affective Neuroscience, 12, 1402-1413.

A Network Model of the Emotional Brain

Pessoa, L. (2017), Trends in Cognitive Sciences, 21, 357-371.

2016 Publications

Overlapping communities reveal rich structure in large-scale brain networks during rest and task conditions

Najafi, M., Mcmenamin, B.W., Pessoa, L. (2016), Neuroimage, 135, 92-106.

Dynamic networks in the emotional brain

Pessoa, L., McMenamin, B. (2016), Neuroscientist, 23, 383-396.

2015 Publications

An fMRI Pilot Study of Cognitive Reappraisal in Children: Divergent Effects on Brain and Behavior

Dougherty, L.R., Blankenship, S.L., Spechler, P.A., Padmala, S., Pessoa, L. (2015), Journal of Psychopathology and Behavioral Assessment, 37, 634-644.

Complex-system causality in large-scale brain networks: Comment on “Foundational perspectives on causality in large-scale brain networks”

Pessoa, L., Najafi, M. (2015), M. Mannino and S.L. Bressler. Physics of Life Reviews, 15, 124-127.

Reward learning and negative emotion during rapid attentional competition

Yokoyama, T., Padmala, S., Pessoa L. (2015), Frontiers in Psychology, 6, 269.

The neurobiology of emotion-cognition interactions: fundamental questions and strategies for future research

Okon-Singer, H., Hendler, T., Pessoa, L., Shackman, A.J. (2015), Frontiers in Human Neuroscience, 9, 58.

Counteracting effect of threat on reward enhancements during working memory

Choi, J.M., Padmala, S., Pessoa, L. (2015), Cognition and Emotion, 29, 1517-1526.

Multiple influences of reward on perception and attention

Pessoa, L. (2015), Visual Cognition, 23, 272-290.

2014 Publications

Impact of appetitive and aversive outcomes on brain responses: Linking the animal and human literatures

Bissonette, G.B., Gentry R.N., Padmala S., Pessoa L., Roesch M.R. (2014), Frontiers in Systems Neuroscience, 8.

Précis of The Cognitive-Emotional Brain

Pessoa, L. (2014), Behavioral and Brain Sciences, 38, 1-66.

Network organization unfolds over time during periods of anxious anticipation

McMenamin, B., Langeslag, S., Sirbu, M., Padmala, S., Pessoa, L. (2014), The Journal of Neuroscience, 34, 11261-11273.

Mechanisms of motivation-cognition interaction: challenges and opportunities

Braver, T.S., …………., Pessoa, L., Samanez-Larkin, G.R., Somerville, L.H. (2014), Cognitive, Affective, & Behavioral Neuroscience, 14, 443-472.

Understanding brain networks and brain organization

Pessoa, L. (2014) Physics of Life Reviews, 11, 400-435.

Motivation versus aversive processing during perception

Padmala, S., Pessoa, L. (2014), Emotion, 14, 450-454.

2013 Publications

Beyond the Tripartite Cognition–Emotion–Interoception Model of the Human Insular Cortex

Uddin, L.Q., Kinnison, J., Pessoa, L., Anderson, M.L. (2013), Journal of Cognitive Neuroscience, 26, 16-27.

Interactions between reward and threat during visual processing

Hu, K., Padmala, S., Pessoa, L. (2013), Neuropsychologia, 51, 1763-1772.

Pervasive competition between threat and reward in the brain

Choi, J.M., Padmala, S., Spechler, P., Pessoa, L. (2013), Social Cognitive and Affective Neuroscience, 51, 1763-1772.

Describing functional diversity of brain regions and brain networks

Anderson, M.L., Kinnison, J., Pessoa, L. (2013), NeuroImage, 73, 50-58.

2012 Publications

Beyond brain regions: Network perspective of cognition–emotion interactions

Pessoa, L. (2012), Behavioral and Brain Sciences, 35, 158-159.

Network analysis reveals increased integration during emotional and motivational processing

Kinnison, J., Padmala, S., Choi, J.M., Pessoa, L. (2012), The Journal of Neuroscience, 32, 8361-8372.

Impact of state anxiety on the interaction between threat monitoring and cognition

Choi, J.M., Padmala, S., Luiz Pessoa, L. (2012), Neuroimage, 59, 1912-1923.

Threat of Bodily Harm Has Opposing Effects on Cognition

Hu, K., Bauer, A., Padmala, S., Pessoa, L. (2012), Emotion, 12, 28-32.

Interactions between cognition and emotion during response inhibition.

Pessoa, L., Padmala, S., Kenzer, A., Bauer, A. (2012), Emotion, 12, 192-197.

2011 Publications

Negative Emotion Impairs Conflict-Driven Executive Control

Padmala, S., Bauer, A., Pessoa, L. (2011), Frontiers in Emotion Science, 2, 192.

Reward reduces conflict by enhancing attentional control and biasing visual cortical processing

Padmala, S., Pessoa, L. (2011), Journal of Cognitive Neuroscience, 23, 3419-3432.

2010 Publications

Emergent processes in cognitive-emotional interactions

Pessoa, L. (2010), Dialogues in Clinical Neuroscience, 12, 433-448.

Emotion and attention effects: Is it all a matter of timing? Not yet.

Pessoa L. (2010), Frontiers in Human Neuroscience, 4, 172.

Pulvinar and affective significance: responses track moment-to-moment stimulus visibility

Padmala, S., Lim, S., Pessoa, L. (2010), Frontiers in Human Neuroscience, 4, 64.

Embedding reward signals into perception and cognition

Pessoa L., Engelmann, J.B. (2010), Frontiers Neuroscience, 4, 17.

Moment-to-moment fluctuations in fMRI amplitude and inter-region coupling are predictive of inhibitory performance

Padmala, S., Pessoa, L. (2010), Cognitive, Affective, and Behavioral Neuroscience, 10, 279-297.

Emotion affects action: Midcingulate cortex as a pivotal node of interaction between negative emotion and motor signals

Pereira, M.G., de Oliveira, L., Erthal, F.S., Joffily, M., Mocaiber, I.F., Volchan, E., Pessoa, L. (2010), Cognitive, Affective, and Behavioral Neuroscience, 10, 94-106.

Attention and Emotion

Pessoa, L. (2010), Scholarpedia, 5, 6314.

Interactions between cognition and motivation during response inhibition

Padmala, S., Pessoa, L. (2010), Neuropsychologia, 48, 558-565.

2009 Publications

Segregating the significant from the mundane on a moment-to-moment basis via direct and indirect amygdala contributions

Lim, S., Padmala, S., Pessoa L. (2009), Proceeding of the National Academy of Sciences, 106, 16841-16846.

Affective learning enhances activity and functional connectivity in early visual cortex

Damaraju, E., Huang, Y.M., Barrett, L.F., Pessoa, L. (2009), Neuropsychologia, 47, 2480-2487.

How do emotion and motivation direct executive control?

Pessoa L. (2009), Trends in Cognitive Sciences, 13, 160-166.

Combined effects of attention and motivation on visual task performance: transient and sustained motivational effects

Engelmann, J.B., Damaraju, E., Padmala, S., Pessoa, L. (2009), Frontiers in Human Neuroscience, 3, 4.

Ungerleider LG. Individual differences in valence modulation of face-selective M170 response

Japee, S., Crocker, L., Carver, F., Pessoa, L. (2009), Emotion, 9, 59-69.

The prefrontal cortex and the executive control of attention

Rossi, A.F., Pessoa, L., Desimone, R., Ungerleider, L.G. (2009), Experimental Brain Research, 192, 489-497.

Attentional control during the transient updating of cue information

Pessoa, L., Rossi, A., Japee, S., Desimone, R., Ungerleider, L.G. (2009), Brain Research, 1247, 149-158.

2008 Publications

What and where pathways

Engerleider, L.G., Pessoa, L. (2008), Scholarpedia, 3, 5342.

Affective learning increases sensitivity to graded emotional faces

Lim, S., Pessoa L. (2008), Emotion, 8, 96-103.

Depth of facial expression processing depends on stimulus visibility: Behavioral and electrophysiological evidence of priming effects

Hsu, S., Hetrick, W.P., Pessoa, L. (2008), Cognitive Affective and Behavioral Neuroscience, 8, 282-292.

Affective learning enhances visual detection and responses in primary visual cortex

Padmala, S., Pessoa, L. (2008), Journal of Neuroscience, 28, 6202-6210.

On the relationship between emotion and cognition

Pessoa, L. (2008), Nature Reviews Neuroscience, 9, 148-158.

Affective learning modulates spatial competition during low-load conditions

Lim, S., Padmala, S., Pessoa, L. (2008), Neuropsychologia, 46, 1267-1278.

2007 Publications

Bihemispheric Leftward Bias in a Visuospatial Attention- Related Network

Siman-Tov, T., Mendelsohn, A., Schonberg, T., Avidan, G., Podlipsky, I., Pessoa, L. (2007) Gadoth N, Ungerleider LG, Hendler T. The Journal of Neuroscience, 27, 11271-11278.

Modulation of emotion by cognition and cognition by emotion

Blair, K.S., Smith, B.W., Mitchell, D.G., Morton, J., Vythilingam, M., Pessoa, L., Fridberg, D., Zametkin, A., Sturman, D., Nelson, E.E., Drevets, W.C., Pine, D.S., Martin, A., Blair, R.J. (2007), Neuroimage, 35, 430-440.

Motivation sharpens exogenous spatial attention

Engelmann, J., Pessoa, L. (2007), Emotion, 7, 668-674.

Neural correlates of perceptual choice and decision making in Fear-Disgust discrimination

Thielscher, A., Pessoa, L. (2007), The Journal of Neuroscience, 27, 2908-2917.

2006 Publications

Sustained and transient modulation of performance induced by emotional picture viewing

Pereira, M.G., Volchan, E., de Souza, G.G., Oliveira, L., Campagnoli, R., Pinheiro, W.W., & Pessoa, L. (2006), Emotion, 6, 622-634. .

Target visibility and visual awareness modulate amygdala responses to fearful faces

Pessoa, L., Japee, S., Sturman, D., Ungerleider, L.G. (2006), Cerebral Cortex, 16, 366-375.

2005 Publications

Load-dependent modulation of affective picture processing

Erthal, F.S., De Oliveira, L., Mocaiber, I., Pereira, M.G., Machado-Pinheiro, W., Volchan, E., & Pessoa, L. (2005), Cognitive, Affective and Behavioral Neuroscience, 5, 388-395.

Quantitative prediction of perceptual decisions during near-threshold fear detection

Pessoa, L., Padmala, S. (2005), Proceedings of the National Academy of Sciences, 102, 5612-5617.

To what extent are emotional stimuli processed without attention and awareness?

Pessoa, L. (2005), Current Opinion of Neurobiology, 15, 188-196..

Visual attention and emotional perception

Pessoa, L., Ungerleider, L.G. (2005), Neurobiology of Attention.

Visual awareness and the detection of fearful faces

Pessoa, L., Japee, S., Ungerleider, L.G. (2005), Emotion, 5, 243-247.

2004 Publications

Top-down mechanisms for working memory and attentional processes

Pessoa, L., Ungerleider, L.G. (2004), The New Cognitive Neurosciences, 919-830.

Neuroimaging studies of attention and the processing of emotion-laden stimuli

Pessoa, L., Ungerleider, L.G. (2004), Progress in Brain Research, 144, 171-82.

Repetition suppression of faces is modulated by emotion

Ishai, A., Pessoa, L., Bikle, C., Ungerleider, L.G. (2004), Proceedings of the National Academy of Sciences, 101, 9827-9832.

Neural correlates of change detection and change blindness in visual working memory.

Pessoa, L., Ungerleider, L.G. (2004), Cerebral Cortex, 14, 511-520.

2003 Publications

Neuroimaging studies of attention: From modulation of sensory processing to top-down control

Pessoa, L. , Kastner, S., & Ungerleider, L.G. (2003), Journal of Neuroscience, 23, 3990-3998. .

Contributions of stimulus valence and arousal to visual system activation during emotional perception fMRI

Mourão-Miranda, J., Volchan, E., Moll, J., de Oliveira-Souza, R., Oliveira, L., Bramati, I., Gattass, R., & Pessoa, L. (2003), Neuroimage , 20, 1955-1963. .

2002 Publications

Neural correlates of visual working memory: fMRI amplitude predicts task performance

Pessoa, L. , Gutierrez, E., Bandettini, P.B., & Ungerleider, L.G (2002),  Neuron, 35, 975-987. .

Neural processing of emotional faces requires attention

Pessoa, L. , McKenna, M., Gutierrez, E., & Ungerleider, L.G (2002), Proceedings of the National Academy of Sciences, USA, 99, 11458-11463. .

Contour integration in the primary visual cortex of the opossum

Oliveira, L., Volchan, E., Pessoa, L. , Marques, R.F., Pantoja, J.H.; Joffily, M., Souza-Neto, D., & Rocha-Miranda, C.E (2002), NeuroReport, 13, 2001-2004..

Attentional control of the processing of neutral and emotional stimuli

Pessoa, L. , Kastner, S., & Ungerleider. L.G (2002), Cognitive Brain Research, 15, 31-45. .

1995-2001 Publications

Visual filling-in for computing perceptual surface properties

Neumann, H., Pessoa, L. , & Hansen, T (2001), Biological Cybernetics, 85, 355-369..

Beyond the grand illusion: what change blindness really teaches us about vision

Noë A, Pessoa L. & Thompson, E. (2000), Visual Cognition, 7, 93-106. .

Lightness from contrast: A selective integration model

Author aRoss, W., & Pessoa, L. (2000), Perception & Psychophysics, 62, 1160-1181.. nd Publication Information

Attentional strategies for object recognition

Pessoa, L. , Exel, S. (1999), Lecture Notes in Computer Science, 1606, 850-859..

Interaction of ON and OFF pathways for visual contrast measurement

Neumann, H., Pessoa, L. , & Hansen, T. (1999), Biological Cybernetics, 81, 515-32..

Complex cell prototype representation for face recognition

Pessoa, L. & Leitão, AP (1999), IEEE Transactions on Neural Networks, 10, 1528-1531..

A neural network architecture of brightness perception: Non-linear contrast detection and geometry-driven diffusion

Neumann, H., Pessoa, L. , & Mingolla, E. (1998), Image and Vision Computing, 16, 423-446..

Texture segregation, surface representation, and figure-ground separation

Grossberg, S., & Pessoa, L. (1998), Vision Research, 38, 2657-2684..

Finding out about filling-in: A guide to perceptual completion for visual science and the philosophy of perception

Pessoa, L. , Thompson, E., & Noë, A. (1998), Behavioral and Brain Sciences, 21, 65-144. .

The perception of lightness in 3-D curved objects

Pessoa, L. , Mingolla, E., & Arend, L. (1996), Perception & Psychophysics, 58, 1293-1305..

Perceived texture segregation in chromatic element-arrangement patterns: High intensity interference

Pessoa, L. , Beck, J., & Mingolla, E. (1996), Vision Research, 36, 1745-1760..

Mach bands: How many models are possible? Recent experimental findings and modeling attempts

Pessoa, L. (1996), Vision Research, 36, 3205-3227.. erception, 25, 425-442..

A contrast- and luminance-driven multiscale network model of brightness perception

Pessoa, L. , Mingolla, E., and Neumann, H. (1995), Vision Research, 35, 2201-2223..